TERATOGENIC EFFECTS OF PANTOTHENIC ACID ANTAGONISTS ON ANIMAL EMBRYOS

Teratogenic effects of pantothenic acid antagonists on animal embryos.

In 1946 Nelson and Evans (1) reported that pantothenic acid (PaA) deficiency in rats often resulted in the fetal death with resorption, and suggested the importance of vitamins in the development of embryos. Lefebvres-Boisselot (2) observed a high incidence of cerebral and ocular defects, digital hemor rhages and edema in the fetuses from PaA-deficient rats. In 1948 Ackermann and Taylor (3) fir...

TERATOGENIC EFFECTS OF LITHIUM CARBONATE ON DEVELOPMENT OF MOUSE EMBRYOS

Teratogenic effects of calcium salts on chick embryos.

This investigation began as an attempt to protect chick embryos from the teratogenic effects of hypoxia by means of exogenously applied calcium pantothenate. The attempt was not only a failure, but it appeared that the compound alone was highly teratogenic. Since it was disturbing to consider that a vitamin, in low dosage, was teratogenic, the phenomenon was studied further by injecting equival...

Teratogenic effects of trypan blue on hamster embryos.

L I T T L E information is available in the literature on the susceptibility of the hamster embryo to teratogens. Desoxycorticosterone acetate apparently has some teratogenic activity (Tedford & Risely, 1950), but the degree and type of abnormality produced by this agent in the hamster have not been recorded. Orsini (1952) has described naturally-occurring urogenital anomalies which appear in f...

Teratogenic effects of ethanol vapour exposure on chick embryos.

OBJECTIVE To observe the effect of ethanol vapours on chick embryos regarding developmental defects and hatchability characteristics. METHODS An experimental study was performed in the Department of Anatomy at the Regional Center of College of Physicians and Surgeons, Islamabad, from February, 2006 to February, 2007. Chicken eggs after having been exposed to ethanol vapours produced in a spec...